This Sim wants to be a jack-of-all-trades. High job skills are extremely desired.
Family
This Sim wants to pull a Liquid Snake and follow what its primal instinct tells it to do.
Romance
This Sim wants to follow what its genes tell it to do, but use protection. Also this Sim may want many lovers, and probably no children.
Popularity
A lot of friends, but no romance. This Sim wants to be known throughout the neighborhood.
Grow Up
This is the 6th aspiration, but Sims can not choose it. It is only available to Toddlers and Children
Pleasure
This is a new Aspiration that was added in the NightLife Expansion. It focuses on the pleasures of love, datings and fun.
Grilled cheese
With only one focus in life ... and that is to east 200 Grilled cheese
No aspirations are mutually exclusive. A Sim with Popularity may want to gain specific skill points. A Knowledgeable Sim may still want a family. The aspiration simply says what Wants are more dominant.
Knowledge
Max all skills
Become hospital chief of staff (Medicine career)
Become Cult leader (Paranormal career)*
Become ecological leader (Natural scientist career)